Simulation models are widely used in urban drainage engineering and research, but they are known to include errors and uncertainties that are not yet fully realised.Within the herein developed framework, we investigate model adequacy across multiple sites by comparing model results with measurements for three model objectives, namely surcharges (wa
A term Total Crossing Time (TCT) is coined in this study.TCT of a pedestrian includes the time spent by the pedestrian in waiting and his/her crossing of a road.This paper argues that considering a distribution of TCT is required for analysis instead of analyzing a crisp value of TCT of pedestrians.This study quantifies, perhaps for the first time,
Background: NLRP3 inflammasome contributes a lot to sterile inflammatory response and pyroptosis in ischemia/reperfusion (I/R) injury.Cardiac fibroblasts (CFs) are regarded as semi-professional inflammatory cells and they exert an immunomodulatory role in heart.Iguratimod provides a protective role in several human diseases through exerting a power